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Malaria Host-Pathogen Interaction Center (MaHPIC)

How do eukaryotic genomes evolve? Our lab is interested in parasite genomics and the biology of genome evolution. The genomes of parasitic eukaryotes are often highly-reduced, devoid of recognizable mobile elements and riddled with intracellular and lateral gene transfers. Our approach is to apply molecular, computational and phylogenetic tools to the analysis of parasite genomes. Projects include the development of tools for data integration, data mining, comparative genomics and the systems biology of host-pathogen interactions. Research focuses on Toxoplasma gondii, Cryptosporidium species and Plasmodium species. Researchers in our group work at the bench, at the computer, or both.

Undergraduate research Garrett Cooper joins the research group. Welcome!
Lab publishes Cryptosporidium enrichment protocol. The work represents several years of development with the late Steve Upton. doi:/10.1016/j.molbiopara.2017.12.004
Shubham Basu graduates with his Master’s in Bioinformatics. Congratulations! He is busy interviewing for positions.
MicrobiomeDB is released. Woohoo! doi:10.1093/nar/gkx1027
Megan DeBarry says goodbye way too soon. You will be missed!
Cool collaboration with the Sinai Lab reveals plasticity of cell-cycle regulation in Toxoplasma. doi:10.1128/mBio.01846-17
MaHPIC publishes a major finding implicating monocytes in the disruption of erythropoiesis during acute malaria in macaques. doi:10.1186/s12936-017-2029-z
Undergraduate researcher Hannah Stealey heads back to school. You will be missed!
The MaHPIC research team implements a new framework to facilitate very fast mining of omics and clinical data in a relational framework. Good Job everyone! arXiv:1706.07992
The MaHPIC team published a really neat Pac-Bio Hi-C correct P. knowlesi genome sequence assembly and annotation. doi:10.1128/genomeA.00883-16
Bill & Melinda Gates award a grant to David Roos and the EuPathDB team to apply our framework to Clinical and epidemiological data mining! Exciting!
Megan DeBarry joins the lab to help us out, short-term, with a data crunch. Thank you!
Undergraduate researcher Hannah Stealey joins the research group. Welcome!
Ousman Mahmud has first paper from his thesis published. It is about apicomplexan sugar transporters. doi: 10.1155/2017/1707231 Yippie!
The group says goodbye to Suman Pakala. He has supported the MaHPIC data validation effort for the last 4 years. We wish him all the best with his new position at UGA.
The Research group says goodbye to Betsy Wenthe. Her administrative talents supported the group through many a storm in her nearly 8 years with the group. She will be missed greatly. Her family on the other hand got Mommy back and for that we are all happy!
The Research group welcomes Rachel Hatfield as our new Administrative Specialist. Welcome aboard!
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Contact:    Last modified: Wednesday, 03-Jan-2018 22:10:51 EST
The Center for Tropical & Emerging Global Diseases & Department of Genetics
University of Georgia, 500 D.W. Brooks Drive, 145 Paul D. Coverdell Center. Athens, GA 30602-7399