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Data Integration - How can we make sense of all the data?

Figure E
Figure E
 

 

Half of the research group is dedicated to the Eukaryotic Pathogen, Vector & Host Informatics Resources Center, VEuPathDB.org (Figure E). We, WS Annotations Group, also work on the development of ontology terms and web service to enhance parasitology research and the automation of work flows, for example by making Galaxy Web Service aware (Figure F).

Figure F
Figure F

Gene Regulation in Cryptosporidium

Figure A
Figure G
 

Which genes are coordinately regulated during the first 72 hours of the in vitro life cycle? (Figure G) and do coordinately regulated genes contain shared motifs? (Figures H-I). Which of these motifs are shared with other apicomplexan species?

 

Figure A
Figure H
Figure A
Figure I

 

Data Mining for New Diagnostic Targets

Figure A
Figure J
Figure A
Figure K
 
How can all the emerging genomic and functional genomic data be exploited to develop better diagnostic targets? (Figure J-K)

The Mitochondrial Genome of Toxoplasma gondii

Figure M
Figure L
 
The mitochondrial genome of this species appears to be different from other apicomplexan species in that it exists in many different permutations and >10,000 fragments of the mitochondrial genome have also been inserted into the nuclear genome (Figure L).
 
 
 
 
 
 
 
 
 
 
 
 
 

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